Uncovering the genetics of skeletal muscle growth and regeneration

ScienceDaily | 3/8/2018 | Staff
lhumara (Posted by) Level 3
"A major hindrance in the development of effective therapies for skeletal muscle diseases thus far has been a lack of understanding of the biological processes that promote muscle growth and repair," said corresponding author Vandana Gupta, PhD, of the Division of Genetics at BWH. "Our study is one of the first efforts to provide specificity to the processes controlling protein synthesis in muscles, which will hopefully allow for the development of effective targeted treatments for skeletal muscle diseases."

Loss of muscle mass is a debilitating feature that is a common manifestation of a wide array of diseases, and leads to reduced muscle function and increased morbidity and mortality. Maintenance of skeletal mass relies on a dynamic balance between protein synthesis and degradation. A number of conditions such as myopathies, sarcopenia, cancer cachexia, disuse atrophy, sepsis and chronic kidney diseases lead to a...
(Excerpt) Read more at: ScienceDaily
Wake Up To Breaking News!
Sign In or Register to comment.

Welcome to Long Room!

Where The World Finds Its News!