The study, newly published in the journal of Neurobiology of Learning and Memory, finds that running mitigates the negative impacts chronic stress has on the hippocampus, the part of the brain responsible for learning and memory.
"Exercise is a simple and cost-effective way to eliminate the negative impacts on memory of chronic stress," said study lead author Jeff Edwards, associate professor of physiology and developmental biology at BYU.
Hippocampus - Memory - Formation - Occur - Synapses
Inside the hippocampus, memory formation and recall occur optimally when the synapses or connections between neurons are strengthened over time. That process of synaptic strengthening is called long-term potentiation (LTP). Chronic or prolonged stress weakens the synapses, which decreases LTP and ultimately impacts memory. Edwards' study found that when exercise co-occurs with stress, LTP levels are not decreased, but remain normal.
To learn this, Edwards carried out experiments with mice. One group of mice used running wheels over a 4-week period (averaging 5 km ran per day) while another set of mice was left sedentary. Half of each group was then exposed to stress-inducing situations, such...
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