The formation and refinement of neural networks is known to be often an activity-dependent process, but mechanisms and nature of activity are not yet clearly understood.
During neuronal circuit formation, afferent axons often make multiple, exuberant, or aberrant connections, which are later eliminated, sometimes in an activity-dependent manner. Such examples are widely seen throughout the central and peripheral nervous systems.
Finding - Research - Group - Fumitaka - Kimura
The finding made by a research group led by Fumitaka Kimura, associate professor at the Graduate School of Medicine, Osaka University indicates that such exuberant early thalamocortical connections are not useless, unnecessary connections but serve to help...
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