Programmable nests for cells

phys.org | 9/20/2019 | Staff
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Using DNA, small silica particles, and carbon nanotubes, researchers of Karlsruhe Institute of Technology (KIT) have developed novel programmable nanocomposites that can be tailored to various applications and programmed to degrade quickly and gently. For medical applications, they can create environments in which human stem cells can settle down and develop further. Additionally, they are suited for the setup of biohybrid systems to produce power, for instance. The results are presented in Nature Communications and on the bioRxiv platform.

Stem cells are cultivated for fundamental research and development of effective therapies against severe diseases, i.e., to replace damaged tissue. However, stem cells will only form healthy tissue in an adequate environment. For the formation of three-dimensional tissue structures, materials are needed that support cell functions with perfect elasticity. New programmable materials suited for use as substrates in biomedical applications have now been developed by the group of Professor Christof M. Niemeyer of the Institute for Biological Interfaces, together with colleagues from the Institute of Mechanical Process Engineering and Mechanics, the Zoological Institute, and the Institute of Functional Interfaces of KIT. These materials can be used among others to create environments in which human stem cells can settle down and further develop.

Researchers - Nature - Communications - Materials - Consist

As reported by the researchers in Nature Communications, the new materials consist of DNA, small silica particles,...
(Excerpt) Read more at: phys.org
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