Clinicians use cognitive tests to screen patients for dementia, but they aren't always able to predict which patients with mild cognitive impairment will develop Alzheimer's disease.
Another test, which measures ability to identify odors, is also used to identify dementia, and this test can be abnormal in both Alzheimer's and other forms of dementia.
Screening - Test - Patients - Problems - Alzheimer
Without a definitive screening test to predict which patients with mild cognitive problems will develop Alzheimer's disease, many individuals often undergo difficult and expensive diagnostic workups.
"No one has looked previously at whether performing well on both the odor identification test and global cognitive performance tests is better at predicting a low risk of cognitive decline or development of Alzheimer's disease," says D. P. Devanand, MBBS, MD, lead author of the paper, professor of psychiatry (in Neurology and in the Gertrude H. Sergievsky Center) at Columbia University Vagelos College of Physicians and Surgeons, and Research Psychiatrist at the New York State Psychiatric Institute. "If we could accurately identify individuals who are unlikely to experience cognitive decline and Alzheimer's disease, we would reduce the need for unnecessary diagnostic investigation with PET imaging and lumbar puncture, which can be cumbersome and expensive, and improve selection of patients for clinical trials, including possibly prevention trials."
Researchers - Data - Adults - Impairment - Dementia
The researchers analyzed data from 749 older adults with mild cognitive impairment without dementia in an urban community who completed a brief cognitive screening test and a 40-item smell identification...
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