Could cannabis oil combat antibiotic resistance? CBD 'boost effectiveness of the drugs'

Mail Online | 10/11/2019 | Connor Boyd Health Reporter For Mailonline
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It's said to fight off anxiety, muscle aches and insomnia - but now a study suggests CBD oil may also hold the key to fighting superbugs.

Researchers have found the trendy health supplement can strip away the ability of bacteria to resist being killed by antibiotics.

Bacteria - Release - Compounds - Nutrients - Defence

Bacteria release tiny compounds which help them transport nutrients and build up a defence to medications.

But CBD oil – part of a booming market in the UK and US – was shown to prevent E. Coli from producing the so-called outer membrane vesicles (OMVs).

Ability - Antibiotics - Bacteria - University - Westminster

This boosted the ability of antibiotics to kill off the bacteria and stop them from multiplying, the University of Westminster researchers claim.

CBD has long been believed to have anti-bacterial properties, but it was not clear how this mechanism worked.

Scientists - Production - OMVs - Bacteria - Defence

Now scientists believe by inhibiting the production of OMVs, it breaks down bacteria's defence and allows the body to fight it off. But experts say trials in humans are now needed to investigate further.

Health bosses have repeatedly warned antimicrobial resistance (AMR) is the biggest threat to modern medicine.

Bacteria - Learn - Drug - People - Doses

Bacteria learn to adapt and become drug resistant when people take incorrect doses of antibiotics or if they are given out unnecessarily.

The problem is propelled by the fact that no new antibiotics have been developed in decades.

People - Infections - Tuberculosis - TB - HIV

Around 700,000 people already die yearly due to drug-resistant infections including tuberculosis (TB), HIV and malaria across the world.

Public Health England says around 5,000 in England die due to superbugs every year.

Researchers - Dr - Sigrun - Lange - Lecturer

Researchers led by Dr Sigrun Lange, a senior lecturer in molecular pathology, grew E. Coli in a laboratory and treated the bacteria with antibiotics.

They applied one micrometre of cannabidiol to the bacteria and assessed what effect it had after an hour.

Dose - Micrometres - CBD - Oil

They then did the same with a higher dose, five micrometres, of CBD oil.

(Excerpt) Read more at: Mail Online
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