Permian lizard-like animal suffered from a bone condition similar to Paget's disease

phys.org | 8/7/2019 | Staff
PaMe (Posted by) Level 3
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A lizard-like animal that lived 289 million years ago suffered from a bone condition similar to Paget's disease, according to a study published August 7, 2019 in the open-access journal PLOS ONE by Yara Haridy of the Museum für Naturkunde in Berlin and colleagues. This is the most ancient known case of such a disease.

The animal in question belonged to an extinct group of lizard-like creatures called varanopids, relatives of the earliest ancestors of mammals or reptiles. The authors identified the disease in an isolated pair of tail vertebrae discovered in an Early Permian cave at Richards Spur, Oklahoma. Micro-CT scanning allowed examination of both the external and internal structure of the elements, revealing that in some places the bone had been thinned by abnormally high levels of reabsorption, while in other areas excessive bone growth had resulted in abnormal bone thickening and the ultimate fusion of the two vertebrae.

Researchers - Condition - Disease - Bone - Disorder

According to the researchers, this condition is most similar to Paget's disease, a bone metabolic disorder marked by a breakdown in communication between bone building cells and bone destroying cells. Paget's disease is commonly seen today in the hips and vertebrae of humans and has been diagnosed in other living mammals and...
(Excerpt) Read more at: phys.org
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