Spacer protects healthy organs from radiation exposure during particle therapy

ScienceDaily | 8/5/2019 | Staff
idkwatitis (Posted by) Level 3
Neskeep received pharmaceutical approval in December 2018 and is available to purchase from June 27, 2019.

Radiation therapy, which is one of the less invasive and less stressful treatments, has been recognized as an important cancer treatment. Health insurance from the Japanese government covers particle therapies for bone and soft tissue tumors, pediatric malignant tumors, and non-squamous head and neck tumors.

Cases - Particle - Therapy - Tumors - Tract

In some cases, it can be difficult to apply particle therapy when malignant tumors are located near digestive tract organs sensitive to radiation (the small and large intestine). Doctors currently use non-absorbent materials such as silicone balloons and Gore-Tex sheets to act as spacers in the abdomen and intestines, or they place the intestine or other organs outside the radiation field using an absorbent mesh. Based on several observations, some patients may then undergo a second surgery to remove the spacer or it may cause serious complications in their bodies for the rest of their lives.

The team succeeded in developing a nonwoven fabric bioabsorbable spacer that can create a space between healthy and cancerous tissues during particle therapy. After that the spacer is safely absorbed by the body.

Neskeep - Fabrics - Acid - Material - Suture

The Neskeep is available in 5, 10 and 15mm nonwoven fabrics using polyglycolic acid, the same material as polyglycolic acid suture thread (Opepolix N (approval code: 16200BZZ01566000) and Opepolix (approval code: 16200BZZ01566000), both already approved for medical use.

In their preclinical evaluation, the team conducted physical experiments to check that the spacer fulfilled the requirements for isolating cancer from organs and providing a barrier against radiation. After safety studies in animal models, a clinical trial was carried out in Kobe University Hospital and Hyogo Ion Beam...
(Excerpt) Read more at: ScienceDaily
Wake Up To Breaking News!
Sign In or Register to comment.

Welcome to Long Room!

Where The World Finds Its News!