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Their filmographries span three decades and they have now hit the streets filming their new collaboration Bliss.
Salma Hayek was in full character while shooting opposite Owen Wilson in Downtown Los Angeles Thursday.
Layers - Isabel - Woman - Streets - World
The 52-year-old dressed in baggy layers to play Isabel, a woman who lives on the streets and is convinced the world around her isn't real.
Her character later meets divorced Greg (Wilson) and their mind-bending love story ensues.
Filming - June - Grown - Ups - Actress
Since filming started in late June, the Grown Ups actress has been seen in the same outfit of a maroon tank top under a long-sleeved blue denim shirt, green pants and thick brown boots, with her hair looking knotted and ratty. She also let a collection of fake chest tattoos peek out from the top of her tank.
Salma was caught having a cigarette between scenes while her co-star got in front of the camera.
Wilson - Outfit
Wilson was wearing an equally dressed down outfit...
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