Are American Zika strains more virulent than Pacific and Asian strains?

ScienceDaily | 6/6/2019 | Staff
baileyboo (Posted by) Level 3
ZIKV is a Flaviviridae family virus carried by infected Aedes mosquitos. It was first isolated in Uganda in the mid-twentieth century but has since spread to Micronesia, Oceania, and most recently South America, Central America, North America and the Caribbean. The strains in each area, however, are distinct; genetic analyses have shown three subtypes -- American, Pacific and Southeast Asian. Previous research has suggested that these subtypes differ in their infectious profiles.

In the new work, Shigeru Tajima, of the Japanese National Institute of Infectious Disease, and colleagues compared the PRVABC59 American subtype, the ZIKV/Hu/Chiba/S36/2016 (ChibaS36) Pacific subtype and the ZIKV/Hu/NIID123/2016 (NIID123) Southeast Asian subtype. They examined the growth rates both in vitro and in mice, and observed...
(Excerpt) Read more at: ScienceDaily
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