Proteins work together to keep strands of DNA free from tangles that could stop them from working

Mail Online | 4/22/2019 | Tim Collins For Mailonline
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A process that cells use to unravel knotted strands of DNA – resembling a method used to control climbing ropes – has been uncovered by scientists.

Experts have identified two sets of proteins that work together to keep the strands unknotted, avoiding tangles that would hamper biological processes.

Breakthrough - Study - Families - Conditions - Cell

The breakthrough study is the first to explain how these two families keep DNA tangle-free under the confined, crowded conditions of the cell.

Dr Davide Michieletto, who led the study, said: 'DNA's long strands might be expected to become horribly tangled – a bit like pulling knotted headphones out of your pocket.

Nature - Machines - Problem - Way - Species

'But instead, nature has created these amazing machines to address this problem in a remarkable way, seemingly across many species.'

The proteins are found in many organisms and scientists believe their role in managing DNA may be common throughout nature.

Family - Proteins - SMC

One family of proteins – known as SMC...
(Excerpt) Read more at: Mail Online
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