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Rather than studying bacteria, the researchers studied viruses that infect pathogenic bacteria, known as bacteriophages, as part of a National Institutes of Health grant to help develop a vaccine against bacterial infection.
"Bacteriophages are typically viewed as bacterial parasites," said Patrick Secor, an assistant professor at UM and a co-author on the paper. "Because of the increasing prevalence of antibiotic-resistant bacteria, people are really getting interested in using bacteriophages (phage therapy) as an alternative to antibiotics to kill pathogenic bacteria."
Bacteriophage - Phage - Therapy - Hosts - Bacteriophages
The bacteriophage used for phage therapy kill their bacterial hosts. Bacteriophages are diverse and considered the most prevalent biological entity on the planet.
"When we looked for bacteriophages that infected the bacterial pathogen Pseudomonas aeruginosa, we found that most strains were infected with bacteriophages called Pf that do not kill their bacterial host," Secor said.
Secor - Researchers - Stanford - University - Pf
When Secor and researchers at Stanford University looked for Pf bacteriophage in human wounds, they were surprised...
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