Masterswitch discovered in body's immune system

ScienceDaily | 2/11/2019 | Staff
Professor Graham Lord, from The University of Manchester, led the study, which could translate into treatments for autoimmune diseases including Cancer, Diabetes, Multiple Sclerosis and Crohn's Disease within a few years.

It is published in the Journal of Clinical Investigation today.

Discovery - Pathway - Molecule - MicroRNA-142 - Advance

The discovery of the molecular pathway regulated by a tiny molecule -- known as microRNA-142 -- is a major advance in our understanding of the immune system.

The 10-year-study found that microRNA-142 controls Regulatory T cells, which modulate the immune system and prevent autoimmune disease. It is, they found, the most highly expressed regulator in the immune system.

Professor - Lord - Research - Kings - College

Professor Lord, led the research while at Kings College London in collaboration with Professor Richard Jenner at UCL.

And according to Professor Lord, the discovery could be translated into a viable drug treatment within a few years.

Autoimmune - Diseases - People - Prime - Life

He said: "Autoimmune diseases often target people in the prime of their life creating a significant socio-economic burden on them. Sometimes, the effect can be devastating, causing terrible hardship and suffering.

"But these findings represent a significant step forward in the understanding of the immune system and we believe many people worldwide...
(Excerpt) Read more at: ScienceDaily
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