Establishment of the immortalized cell line derived from endangered Okinawa rail

phys.org | 11/16/2018 | Staff
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As part of the cellular conservation of endangered species, a research group initiated a primary cell culture project aimed at preserving endangered avian species in Japan, such as the Okinawa rail. However, primary cells cannot be cultured indefinitely because of cellular senescence and stresses caused by cell culture. To overcome these cell culture limitations, primary cells must be immortalized. As a result, the researchers obtained the immortalized avian cells with cell cycle regulation gene expression.

The number of critically endangered animals has been increasing in recent years. According to data from the International Union for the Conservation of Nature (IUCN), 1375 avian species are categorized as being endangered animals, and around 12 percent of the endangered species are avian. The conservation of endangered species is an important task for our next generation in order to maintain genetic diversity. The Okinawa rail, which is a species endemic to northern Okinawa Island, is an example of an endangered (EN) avian species. The Okinawa rail is categorized EN on the IUCN red list, because its individual numbers are estimated to be approximately 1500.

Part - Conservation - Species - Researchers - Cell

As part of the cellular conservation of endangered avian species, the researchers initiated a primary cell culture project aimed at preserving endangered avian species in Japan, such as the Okinawa rail....
(Excerpt) Read more at: phys.org
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