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Cancer cells can develop resistance to the treatments designed to eliminate them. Several studies have linked stress granules (SGs), cell organelles that form transiently in response to extracellular stress, to this phenomenon. However, how SGs protect cancer cells remains unclear.
Susan Wente, Ph.D., and Laura Glass, Ph.D., report their establishment of an experimental cell culture model system to investigate the link between SGs and cell resistance to toxic stress in Advances in Biological Regulation.
System - Investigators - SG - Biology - Subpopulation
Using their system, these investigators discovered altered SG biology in a subpopulation of cells that acquired resistance...
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