"Whole grains are one of the healthiest foods there is. For instance, we know that a high intake of whole grains protects against type 2 diabetes and cardiovascular diseases. Up until now, however, we haven't understood the cellular mechanisms through which a whole grain-rich diet impacts our body," says Dr Kati Hanhineva, Principal Investigator of the study at the University of Eastern Finland.
Using metabolomics analysis, Dr Hanhineva's research group investigated the effects of a whole grain-rich diet on the body's metabolites. The effects were studied in mice fed with bran-rich fodder, and in humans following a diet rich in whole grain products over the course of 12 weeks. A whole grain-rich diet increased the levels of betaine compounds in both mice and humans.
Time - Compounds - Body - Place - Dr
"This is the first time many of these betaine compounds were observed in the human body in the first place," Dr Hanhineva says.
At the end of the 12-week follow-up, the researchers also observed a correlation between improved glucose metabolism and increased presence of betaine compounds in the body.
Acid - Betaine - Example - Levels - Acid
"Pipecolic acid betaine, for example, is particularly interesting. Increased levels of pipecolic acid betaine after the consumption of whole grains was, among other things, associated with lower...
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