Researchers assemble library of sugars | 8/15/2018 | Staff
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Sugar structures called GAGs are present in almost all tissues in the human body, and have important functions in various diseases. The understanding of these sugar structures is limited, because tools to study them have been lacking. Now, researchers from University of Copenhagen have assembled such a tool—a cellular library of sugars.

Most of us tend to think of sugar as a nutritional hazard. However, sugar is an essential component of the human body; it covers the surfaces of our cells and proteins, and tunes the behaviour and function of our tissues in both health and disease.

Glycosaminoglycans - GAGs - Group - Sugars - Tissues

Glycosaminoglycans (GAGs) comprise a group of sugars found in almost all tissues of the human body. Some of these sugars are already being used as blood thinning medication or as a means to prevent inflammation. However, a general understanding of what these sugars do is still lacking. This is partly because researchers have not had effective tools to examine sugars one structure at a time.

Now, researchers from the Copenhagen Center for Glycomics at the University of Copenhagen have successfully mapped the sugar structures in a so-called 'library...
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