The research, conducted by CF-EpiNet -- a Cystic Fibrosis Trust Strategic Research Centre (SRC) of which the University of Liverpool is a member -- has shown that having CF results in lower average birth weight, revealing the need for further research into how CF affects the development of babies in the womb.
The research team compared babies born with and without CF using data on 2.2?million babies in Denmark and Wales. This research, published in July in Thorax, a world-leading respiratory medicine journal, indicates that, while babies with CF are often born prematurely, this only accounts for around 40% of the effect on birth weight. This means that the CF mutation could also have an effect on the way babies develop within the womb. These results may be the first step to understanding and improving the health of babies with CF before they are born.
Findings - Babies - Families - Weight - Birth
The findings further show that babies born to disadvantaged families are likely to have a lower weight at birth, regardless of whether or not they have cystic fibrosis. This indicates that the socio-economic inequalities in outcomes that occur in CF may start in the intrauterine period.
The CF-EpiNet SRC allows researchers to use and enhance the data within the Trust's UK CF Registry to tell us more about what happens when you live with cystic fibrosis. This study has used databases for Wales and Denmark to begin investigating the effects of socio-economic deprivation on outcomes in CF.
Databases - Information - Population - Countries
These databases contain anonymous information from the whole population across these countries.
Poor - Nutrition - Growth
Poor nutrition and slow growth...
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