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The research published in the journal Stem Cell Research and Therapy applies cell transplantation therapy, normally used in bone marrow transplants to treat immunodeficiency disorders.
"There are 70,000 people worldwide living with CF for which there is currently no cure, and disease in the lungs is the major cause of poor health and a significantly shortened life span," says Dr Nigel Farrow, a Post-Doctoral Research Fellow from the University of Adelaide's Robinson Research Institute, who conducted the study alongside Associate Professor David Parsons head of the research team based in the Women's and Children's Hospital.
Australia - Babies - CF - People - Gene
In Australia, one in every 2,500 babies has CF, and one in 25 people carry the defective gene. Even though carriers are not affected by the disorder, they may pass the gene to their children. If both parents are carriers, each of their children has a 1 in 4 chance of being born with the disorder.
"Our research which applies stem cell transplantation, involves harvesting adult stem cells from the lungs of CF patients, correcting them with gene therapy, and then reintroducing those cells back into the patient," says Dr Farrow.
Adult - Stem - Cells - Genes - 'daughter
"The new transplanted adult stem cells pass on their healthy genes to their 'daughter cells' providing a constant means to replenish the airways with healthy cells, and thereby combatting the onset of cystic fibrosis...
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