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A team of international researchers led by Professor Martin Hegner, Investigator in CRANN and Trinity's School of Physics, have developed an automated diagnostic platform that can quantify bleeding – and thrombotic risks – in a single drop of blood, within seconds.
The researchers exploited micro-resonators for real-time measurements of the evolving strength of the blood plasma clot. Along with the clinically measured clotting time, other insightful parameters, from specific factor deficiency to global coagulation parameters (used to assess fibrinolysis), can also be extracted. These technical developments introduce a miniaturised global haemostasis assay with the capability of fine-tuning factor replacement – or anti-coagulation therapies (left image, below).
Collaboration - Hoffman-la-Roche - Researchers - Strategy - Quick
In collaboration with the multinational, Hoffman-la-Roche, the researchers report a novel strategy for quick, reliable and quantitative diagnostics of expression patterns of non-coding short RNA in blood plasma or cell cultures. They directly detect label-free...
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