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A study by the Quantum Technologies for Information Science (QUTIS) group of the UPV/EHU's Department of Physical Chemistry, has produced a series of protocols for quantum sensors that could allow images to be obtained by means of the nuclear magnetic resonance of single biomolecules using a minimal amount of radiation. The results have been published in Physical Review Letters.
Nuclear magnetic resonance (NMR) has a variety of applications, such as medical imaging, neuroscience and detection of drugs and explosives. With the help of quantum sensors, NMR has been adapted to work in the nanoscale regime, where it has the potential to impact disciplines such as life sciences, biology and medicine, and to provide measurements of incomparable precision and sensitivity.
Combination - Sensors - Decoupling - Techniques - NMR
"We expect that the combination of quantum sensors and dynamical decoupling techniques allows NMR imaging of single biomolecules," write authors Dr. Jorge Casanova and Ikerbasque Professor Enrique Solano. This quantum-enhanced NMR "will be able to resolve chemical shifts in tiny picoliter samples, producing biosensors with unparalleled sensitivity and providing new insights into the structure, dynamics, and function of biomolecules and biological processes."
A fundamental tool to improve the sensitivity of NMR setups is to apply large magnetic fields "that polarize our samples, enhance the signal and...
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